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The human body needs selenium to stay healthy. Selenium plays a key role in strengthening immunity, reducing oxidative stress, preventing viral infections and supporting critical illness. Selenium is a trace mineral that is essential for human health and is incorporated into your selenoproteins, which are proteins that perform a variety of functions in the body:
- Immune system: Selenium is important for the immune system and the activation of immune cells.
- Redox homeostasis: Selenoproteins are known for their redox activity and help maintain redox homeostasis.
- Anti-inflammatory properties: Selenoproteins have anti-inflammatory properties.
- Brain function: Selenium is essential for maintaining brain function.
- DNA and cell damage: Selenoproteins help make DNA and protect against cell damage and infections.
- Reproduction: Selenoproteins are involved in reproduction.
- Thyroid hormone metabolism: Selenoproteins are involved in the metabolism of thyroid hormones.
- Wound healing: Some selenoproteins act as antioxidants and inducers during specific phases of wound healing
Selenium deficiency can contribute to various diseases, including cardiovascular disease, cancer, liver disease, and arthropathies. The Tolerable Upper Intake Level (UL) of selenium is 400 mcg per day. High levels of selenium can be dangerous and can interact with some medications. Low levels of selenoprotein P (SELENOP) are associated with cognitive impairment. SELENOP is a transporter of selenium and helps maintain selenium levels in the brain.
A healthcare provider may order a blood or urine test to measure selenium levels in the body if a patient has symptoms of selenium deficiency or toxicity. Symptoms of deficiency include fatigue, mental fog, or weakened immunity, while symptoms of toxicity include garlic breath odor, hair loss, or nail changes. The reference range for serum selenium levels is 120-160 micrograms/liter, but this may vary between labs.
What is Selenium
Selenium forms as many as five different oxidation states. Some are anions, some are neutral and some are cations. Selenium is a trace mineral that the body incorporates into proteins to make over 25 different selenoproteins (like the enzyme glutathione peroxidase). Selenium helps the body produce antioxidant enzymes that protect cells from damage. It’s also important for Thyroid hormone metabolism, DNA synthesis, Reproduction and Protecting the body from oxidative damage and infection. The recommended amount of selenium is 55 mcg per day, and the tolerable upper limit is 400 mcg per day. Consuming too much selenium can be toxic and even fatal.
The talk in geroscience circles over the last fortnight has been all about selenium: can selenium supplements give us the longer healthier life we want? The excitement was sparked by an experiment that found mice given selenium supplements had an improved health span (a longer disease-free period at the end of their lives).
How does this work and might it work on humans? One of the proven methods for increasing health span in many non-humans is by restricting consumption of an amino acid called methionine, which is found in meat and fish. In other words – by following a vegan diet.
How – and why – this happens is complicated (you can read the nitty gritty here). But the researchers involved in this study found that selenium supplementation protected against weight gain and fat accumulation in mice, partly by reducing the amount of circulating leptin, the hormone that makes us feel hungry. Selenium supplementation also appeared to cut levels of an energy-regulating hormone called IGF-1 that, in excess, can reduce our longevity – again no one is quite sure how or why this happens. Excessive IGF-1 can be spurred by a high-protein diet (although apparently cheese is exempt – phew!).
So why not simply follow a vegan diet? Studies of vegans are surprisingly few and far between. But there are a few – and yes, vegans often have fewer diseases of old age, with consistently lower rates of cancer and cardiovascular disease. However, their mortality rates are comparable with vegetarians and sporadic meat eaters. So we’re back to the importance of a plant-based diet.
I digress…back to the mouse study. When I dug a little deeper, it turned out that selenium supplements were doing little more than preventing ‘diet-induced obesity’. Only the fat over-eating mice benefitted. And yet this study of selenium got me thinking: because selenium is clearly affecting certain molecular pathways. Besides, many of us are (apparently) selenium-deficient.
Nor is this the first time selenium has been on the lips of longevity experts. It came to the fore during Covid when low levels were linked to greater severity of illness and a 3-5-fold greater chance of dying.
Since we last wrote about selenium, its role in Covid has been studied in more depth, with the most recent report concluding that:
‘Selenium plays a key role in strengthening immunity, reducing oxidative stress, preventing viral infections and supporting critical illness. Moreover, selenium deficiency is related to oxidative stress and hyperinflammation seen in critical illness, and selenium deficiency is found to be associated with the severity of COVID-19 disease.’
Meanwhile other studies have shown associations between good selenium levels and strong bones. But not when the selenium came from supplements. Supplements had no effect on bone health in two recent studies.
So what to do? Well, ignore any studies on mice. We look at them out of interest – and sometimes they raise intriguing possibilities – but we’d never advise changing your diet based on rodent research.
However, selenium clearly plays a crucial role in supporting our immunity and in amplifying our chances of a healthy lifespan. A recent book suggests many of us have levels of selenium that are between 15 and 40% lower than they should be (so says cardiovascular surgeon, James DiNicolantonio, in his new book The Immunity Fix), partly because of our grossly depleted soil. Which is to indicate that organic produce may contain more selenium.
Glyphosate
Wheat can be a good source of selenoproteins. However, the content of selenium in wheat can range from sufficient to very low, depending upon soil physical conditions. Soil compaction, which results from modern practices of “no till” agriculture (Huggins & Reganold, 2008), can lead to both reduced selenium content and a significant increase in arsenic content in the wheat (Zhao et al., 2007). Since glyphosate has been shown to deplete sulfur in plants (Saes Zobiole et al., 2010), and selenium is in the same column of the periodic table as sulfur, it is likely that glyphosate also disrupts selenium uptake in plants.
The gut bacterium Lactobacillus, which is negatively impacted by glyphosate and depleted in association with celiac disease, is able to fix inorganic selenium into more bioavailable organic forms like selenocysteine and selenomethionine. Selenocysteine is present in the catalytic center of enzymes that protect the thyroid from free radical damage. Free radical damage would lead to apoptosis and an autoimmune response. Glyphosate’s disruption of these bacteria would lead to a depletion in the supply of selenomethionine and selenocysteine. Methionine depletion by glyphosate would further compound this problem.
Thus, there are a variety of ways in which glyphosate would be expected to interfere with the supply of selenoproteins to the body, including its effects on Lactobacillus, its depletion of methionine, the no-till farming methods that are possible because weeds are killed chemically, and the likely interference with plant uptake of inorganic selenium.
Selenium is a trace mineral, which means that the body only needs a small amount of it. It is found naturally in foods or as a supplement. Selenium is an essential component of various enzymes and proteins, called selenoproteins, that help to make DNA and protect against cell damage and infections; these proteins are also involved in reproduction and the metabolism of thyroid hormones. Most selenium in the body is stored in muscle tissue, although the thyroid gland holds the highest concentration of selenium due to various selenoproteins that assist with thyroid function.
Recommended Amounts RDA: The Recommended Dietary Allowance (RDA) for adult men and women 19+ years of age is 55 micrograms daily. Women who are pregnant and lactating need about 60 and 70 micrograms daily, respectively. UL: The Tolerable Upper Intake Level (UL) for selenium for all adults 19+ years of age and pregnant and lactating women is 400 micrograms daily; a UL is the maximum daily intake unlikely to cause harmful effects on health.
Selenium is a component of selenoproteins and enzymes. These have antioxidant properties that help to break down peroxides, which can damage tissues and DNA, leading to inflammation and other health problems. The amount of selenium in foods can vary widely depending on the selenium content of the soil in which it is grown. Soil content varies widely by region. Plant foods obtain selenium from soil, which will then affect the amount of selenium in animals eating those plants. Protein foods from animals are generally good sources of selenium. Seafood, organ meats, and Brazil nuts are the foods highest in selenium although Americans obtain most of their selenium from everyday staples, like breads, cereals, poultry, red meat, and eggs. Brazil nuts Fin fish and shellfish Beef Turkey Chicken Fortified cereals Whole-wheat bread Beans, lentils.
Deficiency
Signs of Deficiency and Toxicity Deficiency A deficiency of selenium in the U.S. is rare as the soil throughout North America is generally rich in selenium. [7] Even if people live in areas with lower-selenium soil, the transport of food across the region as well as the use of fortified foods and supplements reduce the risk of deficiency. Two conditions are associated with severe selenium deficiency: 1) Keshan disease, a type of cardiomyopathy, or disease of heart muscle, and 2) Kashin-Beck disease, a form of osteoarthritis.
Symptoms
- Nausea
- vomiting
- Headaches
- Altered mental state
- Confusion
- Lethargy
- Seizures
Groups at risk for deficiency: People living in low-selenium regions who also eat a primarily plant-based diet. This is rarely seen in the U.S., but populations in China, Russia, and Europe are at risk as their soil is generally low in selenium. The risk is further increased in people living in these areas who eat a vegetarian or vegan diet People with HIV. The virus can lead to diarrhea, malabsorption of nutrients, and decreased appetite. People with kidney failure undergoing dialysis. This mechanical process of filtering the blood can remove some selenium. The dietary restrictions required with kidney failure can also decrease overall food intake, leading to a risk of selenium deficiency.
Toxicity Chronically high intakes of selenium can lead to health problems, ranging from muscle tremors, hair loss, stomach upset, and lightheadedness, to more severe outcomes of heart attack, respiratory distress, or kidney failure. Brazil nuts are exceptionally high in selenium even when grown in low-selenium soil, with even one nut containing more than the RDA. Eating too many of these nuts on a daily basis can reach a toxic level, as well as using supplements that contain selenium in excess of the RDA. Early symptoms: Metallic taste, bad breath Nausea, diarrhea Hair loss Nail brittleness or discoloration Skin rash or lesions Skin flushing Fatigue Irritability Muscle tenderness
Selenium and iodine have a synergistic relationship that is especially important for a healthy thyroid. Iodine is a component of thyroid hormone, and selenium as a selenoprotein helps to convert the thyroid hormone into its active form. Both minerals are needed by the thyroid in adequate amounts; too much of one can contribute to a deficiency of the other. Selenium supplements are promoted to offer several benefits, including boosting immune function, improving hair and nail health, and supporting a healthy thyroid. They are sometimes combined with other antioxidant vitamins such as vitamin E or C. These supplements usually contain between 100-400 micrograms of selenium per dose (the Tolerable Upper intake Level is 400 micrograms). However, if a person is not at high risk for a deficiency, there is no evidence that taking a higher amount of selenium promotes the health benefits shown on these supplement labels.
HIV
HIV infection has been linked to selenium deficiency which, in turn, is thought to be associated with a high risk of tuberculosis and mortality in HIV-infected patients. Furthermore, several trials have reported the beneficial effects of selenium supplementation in patients with HIV
Covid
According to the NIH, Serelnium doesn’t stop Covid. In fact, immediately after the beginning of the COVID-19 pandemic, several speculative reviews suggested that selenium supplementation in the general population could act as a silver bullet to limit or even prevent the disease. Instead, a deep reading of the scientific reports on selenium and COVID-19 that are available to date supports neither the specific role of selenium in COVID-19 severity, nor the role of its supplementation in the prevention disease onset, nor its etiology. They poo-poo’d it. Of course they did.
Among the mineral’s health effects, selenium helps to keep the body healthy and protects against DNA damage. Selenium (Se) is a ubiquitous element akin to sulfur (S) existing in the Earth crust in various organic and inorganic forms. As such, a careful and thorough assessment of the role selenium may play in COVID-19 is certainly justified and may help to guide ongoing public-health decisions. Selenium biochemistry may be a key in understanding how to strengthen the immune system against COVID. Selenium (Se) deficiency has a ‘striking’ yet overlooked link with COVID-19 severity, researchers have argued in a review which outlines a supplementation action.
Crude Oil
“Crude oil selenium deficiency in soil” refers to a situation where the soil has a low concentration of selenium, a vital trace element, which can be partially attributed to the extraction and processing of crude oil, as the process often removes selenium from the soil where oil is extracted, leading to potential deficiencies in plants and animals that rely on that soil for nutrients; essentially, the oil extraction process can deplete the natural selenium levels in the soil. When crude oil is extracted from the ground, it can carry small amounts of selenium with it, leading to a depletion of this element in the surrounding soil. Low selenium levels in soil can result in selenium deficiency in plants grown there, which can then lead to deficiencies in animals that consume those plants.
Heavy Metals
When soil is deficient in selenium, the presence of heavy metals can become even more problematic, as selenium can act as a protective agent against the toxicity of these metals in plants, meaning that low selenium levels can exacerbate the harmful effects of heavy metals like cadmium, lead, and arsenic, potentially leading to increased accumulation of these metals in the food chain when crops are grown in such soil.
Selenium plays a role in plant defense mechanisms, helping to mitigate the uptake and toxicity of heavy metals by regulating root architecture and antioxidant activity within the plant.
When selenium is deficient in soil, plants become more susceptible to accumulating heavy metals from the environment, potentially leading to higher levels of these metals in the edible parts of the crop.
This increased metal accumulation in plants can pose a health risk to humans who consume crops grown in selenium-deficient soil with high heavy metal levels.
Applying selenium fertilizers to soil in areas with selenium deficiency can help mitigate the negative impacts of heavy metals by enhancing plant tolerance and reducing their uptake.
Addressing heavy metal contamination in soil through techniques like phytoremediation or chemical extraction can also be important in areas with both selenium deficiency and heavy metal pollution.
Mad Cow
40 years ago, farmers had a huge problem with Alzheimers in cows. The state called it mad cow’s disease to cover up what it truly was. Now it’s called Keshan disease. Here’s what they did to stop it. They removed vegetable oil and corn oil from feed and added high amounts of vitamin E and trace amounts of selenium. Mad Cow Disease or BSE is caused by an abnormal protein called a prion, which is usually found in the brain. The prion changes shape and triggers a chain reaction that destroys brain cells and nervous system tissue. Cattle become infected by eating feed contaminated with the prion. Selenium deficiency can be caused by a number of factors, including: Low soil selenium levels, Malabsorption, Chronic conditions like HIV infection or chronic alcohol abuse, Pregnancy, and Severe illness.
Treatment
Oral supplementation with selenium, 0.002 to 0.006 mg/kg of body weight, is recommended in selenium deficient areas. Supportive therapy is required for the survival of severely affected cases, however heavy metals in the body can significantly affect selenium levels by depleting them due to the high affinity between the two elements, meaning that heavy metals like aluminum, strontium, cadmium and mercury can bind to selenium and essentially “sequester” it, reducing its bioavailability in the body; however, in some cases, adequate selenium intake can also help mitigate the toxicity of certain heavy metals by forming less harmful complexes with them.
Conclusion
Could there be a selenium deficiency nationwide due to geonegineering, oil drilling, and glyphosate destroying the natural selenium in plants? Academia says American soil is rich in selenium. That’s interesting because a simple google search reports: In the United States, approximately 298 million acres of land are sprayed with glyphosate, the active ingredient in Roundup, each year and over 21 million pounds of glyphosate are used on roadways, in forestry, and for other non-agricultural uses.
Glyphosate use has increased significantly since the mid-1990s:
- 1974–2004: Farmers applied about 27% of the total volume of glyphosate applied since 1974.
- 1996–2000: Agricultural applications of glyphosate rose rapidly as GE-HT crops gained market share.
- 2010: Agriculture’s share of total glyphosate use had risen to 90%.
These numbers don’t match the claims that American soil is rich in selenium because I have found proof that glyphosate kills selenium in plants. The NIH admits it.
That, coupled with drilling oil which removes selenium in soil. The forest service and BLM manages about 23 million acres under lease to oil and gas developers at the end of FY 2022. Under Trump this will grow. This accounts for 10% of all land in the United States that is depleting selenium.
And to top all that off, the amount of aluminum in our soil is 4.67% which absorbs selenium. The typical range of aluminum in soils is from 1 percent to 30 percent (10,000 to 300,000 mg Al kg-1). Now, when we add these numbers up between crude oil, glyphosate and the heavy metals in our soil, we come to these numbers:
- 81% of all Americans have had recent glyphosate exposure according to the FDA
- 10% of all land (where they drill for oil) is depleted of selenium
- Half of all farms use glyphosate on corn, wheat, cotton, soybeans, wheat, oats and fruits.
- And the rest of the soil is contaminated with high levels of aluminum.
Does it take an expert to see those numbers and not panic? If 81% of us have been exposed to glyphosate, which is a real number according to the FDA, wouldn’t it be safe to say that the majority of Americans could be selenium deficient? And if round up, crude oil & heavy metals bind to selenium, wouldn’t those numbers of 81% really be even higher?
Maybe selenium is the key to all our modern day health problems and greed has suppressed this information. Selenium helps brain cells by acting as a potent antioxidant, protecting them from oxidative stress through its role in producing selenoproteins like glutathione peroxidase, which helps neutralize harmful free radicals that can damage brain tissue; this protective effect is crucial for maintaining healthy brain function and may potentially help prevent cognitive decline associated with aging or neurological diseases.
After spending just 8 hours finding this information and comparing to health experts, and asking AI for data, the threat of selenium deficiency is in America is real and no one is talking about it. I never heard about it until I heard a whistleblower mention them using selenium in cow feed to stop Alzheimer’s in cows. If 81% of Americans are exposed to the selenium killer glyphosate and are being inundated with heavy metals through geoengineering, our brains are in a real threat here. Who has these numbers? Who is hiding this from the public? And to think that a simple thing of heavy metal detox and supplementing selenium would keep us healthy is so cheap it’s sickening. It would cost nearly pennies for every American to get the help they need.
And to think that a simple curious hick of a researcher from Oregon stumbled across the story of the century compared to the smartest scientists, medical engineers and the like who overlooked this data is silly, stupid and unnecessary. We have the brains to build a society of health and wellness but we are kept in the dark of crucial information that could save the lives of millions to save the fortunes of a few. the Bible says my people perish due to a lack of knowledge. Isn’t that the truth?
Recent research suggests that worldwide, up to one in seven people are dealing with selenium deficiency. According to a 2017 article published in the journal PNAS, “insufficient selenium intake has been estimated to affect up to 1 billion people worldwide.” Selenium deficiency risk is also predicted to increase under future climate change.
Deficiencies of micronutrients, including essential trace elements, affect up to 3 billion people worldwide. The dietary availability of trace elements is determined largely by their soil concentrations. Until now, the mechanisms governing soil concentrations have been evaluated in small-scale studies, which identify soil physicochemical properties as governing variables. However, global concentrations of trace elements and the factors controlling their distributions are virtually unknown. We used 33,241 soil data points to model recent (1980–1999) global distributions of Selenium (Se), an essential trace element that is required for humans.
Worldwide, up to one in seven people have been estimated to have low dietary Se intake. Contrary to small-scale studies, soil Se concentrations were dominated by climate–soil interactions. Using moderate climate-change scenarios for 2080–2099, we predicted that changes in climate and soil organic carbon content will lead to overall decreased soil Se concentrations, particularly in agricultural areas; these decreases could increase the prevalence of Se deficiency. The importance of climate–soil interactions to Se distributions suggests that other trace elements with similar retention mechanisms will be similarly affected by climate change.
How convenient the scientists who claim 1 in 7 have a selenium deficiency are blaming it on climate change when the culprit is anything but. Glyphosate, heavy metals and crude oil are the issue. Obviously, there is a cover up here. My best guess is overpopulation and the world economic forum’s depopulation agenda. Life is about arming yourself with information and knowledge. If you’re looking to better your health, start taking this as a supplement.
source
Gemini AI
https://pmc.ncbi.nlm.nih.gov/articles/PMC10222736
https://www.pnas.org/doi/full/10.1073/pnas.1611576114